STEM / applied
Advanced synthesis · Graduate · Chemistry
Topics
Laboratory execution
- Air-sensitive reaction setup and Schlenk techniques
- Low-temperature reactions and cryogenic chemistry
- Flash chromatography and preparative HPLC purification
- Reaction optimization: screening, DoE principles
- In-process analytical monitoring (TLC, LCMS)
- Handling hazardous reagents: organolithiums, azides, peroxides
- Process safety in scale-up of synthetic steps
- Documentation for GMP and process chemistry transfer
- Troubleshooting failed reactions and purifications
- Writing experimental sections for publications and patents
Applied synthesis
- Process chemistry in pharmaceutical manufacturing
- Fine chemical and agrochemical synthesis
- Contract manufacturing organization (CMO) workflows
- Green chemistry metrics in route selection
- Cost of goods (COGS) analysis for synthetic routes
- Intellectual property and freedom-to-operate in synthesis
- Automation and high-throughput reaction screening
- Flow chemistry for hazardous transformations
- Academic vs industry synthesis priorities
- Career paths in process, medicinal, and academic synthesis
What each unit includes
Open a unit below for full materials. Typical resources:
- Study guide
- Exam Strategy
- Common Mistakes
- Worksheets
- Word problems
- Mixed Practice
- Multi-Unit Problems
- Review
- Practice test
- Answer key
Study units
Each unit includes a study guide, worksheets, review, practice test, and answer key. One unit is free; subscribe for the full class.
- Retrosynthetic analysis
Disconnection approach and synthon concept
Coming soon - C–C bond formation methods
Palladium-catalyzed cross-coupling: scope and limitations
Coming soon - Heteroatom and functional group chemistry
Selective oxidation and reduction methods
Coming soon - Total synthesis case studies
Classical total syntheses: strychnine, reserpine, morphine
Coming soon - Laboratory execution
Air-sensitive reaction setup and Schlenk techniques
Coming soon - Applied synthesis
Process chemistry in pharmaceutical manufacturing
Coming soon
Pricing calculator
Choose materials, tutoring, or both — or book a single session as needed. Customize your plan on the subscribe page.
$1,162 · Advanced synthesis · 18 tutoring hrs
Study guides, worksheets, reviews, practice tests, and answer keys for 1 class. 18 tutoring hours (1 hr / week · semester). Bundle discount applied vs buying separately. Pay in full via Zelle.