STEM / applied
Toxicology intro · Undergraduate · Chemistry
Learning objectives from the Toxicology intro syllabus, grouped by unit. Click an objective for study materials.
Learning objectives
Click an objective for study materials.
Foundations of toxicology
- History and scope of toxicology — History and scope of toxicology
- Paracelsus principle: dose makes the poison — Paracelsus principle: dose makes the poison
- Types of toxicology: descriptive, mechanistic, regulatory, forensic — Types of toxicology: descriptive, mechanistic, regulatory, forensic
- Exposure routes: oral, dermal, inhalation, injection — Exposure routes: oral, dermal, inhalation, injection
- Absorption, distribution, metabolism, excretion (ADME) of xenobiotics — Absorption, distribution, metabolism, excretion (ADME) of xenobiotics
Dose–response and hazard assessment
- Dose–response curves and threshold concepts — Dose–response curves and threshold concepts
- LD₅₀, LC₅₀, and median effective doses — LD₅₀, LC₅₀, and median effective doses
- No-observed-adverse-effect level (NOAEL) — No-observed-adverse-effect level (NOAEL)
- Reference dose and margin of safety — Reference dose and margin of safety
- Hormesis and low-dose effects (debate) — Hormesis and low-dose effects (debate)
Mechanisms of toxicity
- Electrophilic and nucleophilic toxic reactions — Electrophilic and nucleophilic toxic reactions
- Reactive oxygen species and oxidative stress — Reactive oxygen species and oxidative stress
- Lipid peroxidation and membrane damage — Lipid peroxidation and membrane damage
- DNA adducts, mutations, and carcinogenesis — DNA adducts, mutations, and carcinogenesis
- Cytochrome P450 metabolism and reactive metabolites — Cytochrome P450 metabolism and reactive metabolites
Testing and regulatory toxicology
- In vitro assays: cell culture, Ames test — In vitro assays: cell culture, Ames test
- In vivo animal studies: acute, subchronic, chronic — In vivo animal studies: acute, subchronic, chronic
- Alternative methods: 3Rs (replacement, reduction, refinement) — Alternative methods: 3Rs (replacement, reduction, refinement)
- Epidemiological studies and human evidence — Epidemiological studies and human evidence
- IARC carcinogen classification groups — IARC carcinogen classification groups
What each unit includes
Open a unit below for full materials. Typical resources:
- Study guide
- Exam Strategy
- Common Mistakes
- Worksheets
- Word problems
- Mixed Practice
- Multi-Unit Problems
- Review
- Practice test
- Answer key
Study units
Each unit includes a study guide, worksheets, review, practice test, and answer key. One unit is free; subscribe for the full class.
- Foundations of toxicology
History and scope of toxicology
Coming soon - Dose–response and hazard assessment
Dose–response curves and threshold concepts
Coming soon - Mechanisms of toxicity
Electrophilic and nucleophilic toxic reactions
Coming soon - Testing and regulatory toxicology
In vitro assays: cell culture, Ames test
Coming soon
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$1,162 · Toxicology intro · 18 tutoring hrs
Study guides, worksheets, reviews, practice tests, and answer keys for 1 class. 18 tutoring hours (1 hr / week · semester). Bundle discount applied vs buying separately. Pay in full via Zelle.